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Nexium vs. Prilosec

Although Prilosec and Nexium are very similar, there are also many differences between them. Some of these are price, availability and what they are used to treat. If you're wondering which drug is right for you, read on.

  1. Price

    • Prilosec costs around $20 a month; Nexium costs about $190 a month.

    Over-the-Counter vs. Prescription

    • Prilosec is available over-the-counter; Nexium is available only by prescription.

    Gastric Ulcers

    • Approval has been given to Prilosec to treat gastric ulcers no matter what the cause; Nexium is officially limited to treat gastric ulcers caused by nonsteroidal anti-inflammatory drugs.

    Who Came First

    • Prilosec became available to the public 1988; Nexium came along in 2001.

    Side Effects

    • Prilosec can cause loss of appetite, while Nexium does not.

    For Kids or Not For Kids

    • Nexium may be taken by children, though you should be at least 18 to use Prilosec.

    Length of Treatment

    • Prilosec has a recommended 14-day treatment plan. Nexium is recommended for a much longer 4- to 8-week plan.

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