Side Effects of Benadryl on Dogs

Dogs often have allergies. These allergies cause rashes, sneezing or scratching. When a dog licks itself or rubs its nose on bedding, a veterinarian may recommend an over-the-counter allergy medication such as Benadryl for temporary relief. Benadryl, or diphenhydramine hydrochloride, is generally safe but can have side effects.

  1. Sedation

    • The most common side effect is drowsiness or mild disorientation. Benadryl is sometimes used for this mild tranquilizing effect.

    Vomiting

    • Diphenhydramine is often used to ease vomiting or motion sickness. In some dogs, however, the medication makes the dog throw up and the vet may recommend giving it with food to minimize stomach upset.

    Drug Interaction

    • This antihistamine can interact with medications such as tranquilizers and barbiturates to suppress the natural body functions.

    Lack of Appetite

    • Some dogs are not hungry when taking Benadryl. The veterinarian may recommend feeding the dog before giving the medication.

    Warning

    • Read labels carefully and do not use a medication combining diphenhydramine with a pain reliever or decongestant. The combination drugs can be harmful to dogs.

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