Glutathione has been used by many doctors to treat diseases that destroy neurons, such as Parkinson's disease. Intravenous glutathione can be administered by medical personnel when there is a need to eliminate free radicals in a person's system. Although the side effects are rare, there are specific situations and conditions that may increase the likelihood of unwanted symptoms developing in a patient.
A glutathione IV can create very unpleasant side effects when matched with too much selenium. If a person ingests selenium in levels of 400 milligrams or more in a day, the ions from the metal will merge with glutathione and can cause hair loss, white spots on nails or a loss of feeling in appendages, according to the Agency for Toxic Substances and Disease Registry.
Healthy individuals or people with kidney and liver problems can suffer digestive problems from the injection. A report in the Journal of Nutrition shows these effects can cause serious damage to a person's system and cause severe pains, diarrhea and gas.
If there are too many antioxidants in a person's bloodstream, the effects of a glutathione IV dosage can be completely nullified, according to the Textbook of Cosmetic Dermatology. This means that a person who needs the compound for a condition may not receive any benefits from the injection.
The Aging Studies Institute says that excessive use of a glutathione IV may cause substantial neurological side effects. The drug can be toxic in large dosages, leading to shivers, shakes, anxiety or depression issues. Use of this chemical should always be closely monitored by a medical professional.
Chronic use of glutathione can lead to increased tolerance of the drug, as stated in the Journal of Nutrition. Within six months, a person needs multiple injections daily to obtain the same benefits as were originally present, which can lead to the likelihood of one of the other side effects taking control of the body.