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- Only one skin lightening agent is approved by the Food and Drug Administration (FDA) at the moment. This is called hydroquinone and is used in many skin bleaching creams. However, mercury is another common ingredient in skin whitening creams, which is known to be quite dangerous. Both substances work to lighten the skin.
- Using creams that lighten the skin can make you very sensitive to sunlight. You cannot go outside unprotected while using these creams. Either wear clothing on the areas you've treated or wear a sunblock containing at least SPF 15. Without protection, you may burn within a matter of minutes, so be careful.
- Hydroquinone, in particular, is known to interact with common ingredients included in facial cleansers. Any type of peroxide should not be used at the same time you use a skin lightener. This includes hydrogen peroxide and the common acne fighter benzoyl peroxide. While permanent damage is not likely, using both products in conjunction can cause temporary staining of the skin.
- Hydroquinone-based creams can cause several side effects, most of which are normal and are nothing to worry about. If your skin is a bit red, irritated or itchy following the application of the cream, it is normal. Even a burning or stinging sensation is normal, as long as it dissipates quickly. Mercury-based creams are more damaging, however, and if used for too long can cause poisoning, leading to kidney or liver damage or failure.
- As with any product, some people should not use hydroquinone or mercury skin lightening creams for any reason. Pregnant or nursing women shouldn't use them, as they can get into the bloodstream and cause birth defects. Allergic reactions or contact dermatitis are also possible, causing crusty scabs, severe itching, pain, burning and swelling. If you exhibit signs of an allergic reaction to a skin lightener, contact a health care professional immediately and discontinue use of the cream.
