Hydroxyzine Side Effects


Hydroxyzine is a prescription medicine that is classified as an antihistamine and has both sedative and anticholinergic properties effects. Anticholinergic agents obstruct neurotransmitter acetylcholine effects. Histamine is emitted by the body during various kinds of allergic reactions (and also sometimes with colds). Hydroxyzine is an antihistamine that works to prevent the effects of histamine from taking place and, therefore, to reduce discomfort. Some of histamine's effects include sneezing, nasal congestion, runny nose and itchy nose.Various possible side effects are caused by taking this medication.

Common Side Effects

A couple of common side effects of hydroxyzine exist. These side effects are not considered to be cause for alarm, in general, because they usually go away quickly after the body gets used to this antihistamine. These side effects are dry mouth and drowsiness. If you have either or both of these side effects and find them to be especially long-lasting or bothersome, you need to notify your physician regarding the situation.

Serious Side Effect

Serious side effects of hydroxyzine are far less common than drowsiness and dry mouth. The only serious side effect of this medication, apart from potential allergic reactions, is involuntary movements of the body. This side effect can lead to dangerous consequences, so it is important to seek emergency medical attention if you experience it.

Allergic Reactions

Serious allergic reactions to hydroxyzine are also uncommon. Some signs to look out for are chest tightness or heaviness, problems with breathing, hives, itchiness, skin rash and swelling of the tongue, face, lips, or mouth. If you experience any of these signs, you need to get medical help immediately.


This medication is not necessarily safe or suitable for everybody to use. It is vital to discuss the possibility of taking hydroxyzine with your doctor beforehand. Some people who are often advised against taking hydroxyzine include pregnant females, those with stomach or intestinal blockage, stomach ulcers, glaucoma, epilepsy, kidney or liver disease, urination difficulties, enlarged prostate, thyroid disorder, hypertension, heart disease, emphysema, asthma, or any other kind of respiratory condition. In some cases, these individuals are permitted to take hydroxyzine, but dosage changes are necessary.


Overdosing on any medication could lead to harmful side effects, and hydroxyzine is no exception. If you are worried that you might have taken more than the recommended dosage amount of hydroxyzine, you need to get emergency medical assistance. Some symptoms of hydroxyzine overdose include severe drowsiness, feeling faint, nausea and throwing up.

Drug Interactions

When drug interactions occur, the effectiveness of all of the medications involved is comprised. There are various kinds of medications and substances that could lead to interactions with hydroxyzine. These include alcohol (it enhances its effects of sedation), narcotic pain relievers, tricyclic antidepressants (like imipramine and desipramine), various antihypertensive medicines and certain anti-anxiety (benzodiazepine class) medications. This is why it is important to inform your doctor of any medications and nutritional supplements that you might be taking.

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