Side Effects of Yasminelle Pill


Yasminelle is an oral contraceptive with a low dose of estradiol, a synthetic estrogen, and drospirenone, a synthetic progesterone. Drospirenone is closer to natural progesterone than the synthetic progesterones used in other birth control pills.

Since Yasminelle uses a very low dose of hormones, you are less likely to develop side effects than you would if taking more potent birth control pills. Still, side effects are possible, especially in the first few months after starting the pill.

Initial Symptoms

  • Yasminelle works by making your hormone levels similar to what they would be during pregnancy, which prevents ovulation and changes to the uterine lining. Unfortunately, this can also cause breast tenderness, mood changes, headaches, spotting and nausea. These symptoms usually disappear within three months as your body adjusts to the hormones.

Cardiovascular Disease

  • Taking supplemental estrogen puts you at a higher risk for clotting, which can lead to heart attack and stroke. Since Yasminelle has a very low dose of estradiol it is somewhat safer than pills with higher amounts. Still, if you are a smoker over the age of 35 or have a history of cardiovascular disease, you should seriously consider using a different form of contraception.


  • According to the Mayo Clinic, taking drospirenone and estradiol increases your risk of developing bladder cancer and leukemia. Studies on the link between birth control pills and breast cancer are inconclusive, but it is important to have regularly scheduled mammograms and perform monthly self-examinations while you are on Yasminelle. Report any unusual lumps or discharge to your doctor immediately.


  • Taking oral contraceptives increases your risk of developing hypertension. Have your blood pressure checked regularly while taking Yasminelle to make sure it is staying in a healthy range. If you already have high blood pressure, Yasminelle may not be for you. Talk to your doctor about alternative forms of contraception.

Severe Side Effects

  • If you take Yasminelle or any other type of birth control pills, there are certain side effects you need to look out for. Use the acronym "ACHES" to remember them: abdominal pain, chest pain, headache, eye problems and severe leg pain. Mild cramping and occasional headaches are not a cause for concern, but if you experience severe symptoms you need to contact your doctor immediately.

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