What Are the Side Effects of Buspar?


The generic name of Buspar is buspirone. It is available by prescription only. Buspar is intended to treat anxiety disorders. It works with the chemicals in your brain to reduce symptoms such as irritability, fear, tension, pounding heartbeat and dizziness. However, Buspar is only intended for short-term use. Be aware of all the possible side effects before using Buspar.

Mild Side Effects

  • Buspar may cause some side effects. Some of the more mild possible side effects include drowsiness, restlessness, blurred vision, dizziness, problems with concentration, insomnia, an upset stomach and nausea. If any of these side effects become troublesome for you, talk to your doctor about switching to another medication.

Serious Side Effects

  • Buspar also has the potential to cause more serious side effects. These could include the lack of coordination or balance, unusual thoughts or behavior, a depressed mood, lightheadedness, fainting and an uneven heartbeat. Possible signs of an allergic reaction include problems breathing, hives and facial swelling. If you experience any of these, contact your doctor immediately.


  • Never take more of this medication than instructed by your doctor. If you do happen to take too much of this drug, go to the emergency room. Signs of a possible overdose include stomach pain, blurred vision, nausea, vomiting, drowsiness and dizziness.

Pre-existing Conditions

  • Never use Buspar if you are allergic to buspirone. Additionally, you will be unable to take Buspar if you have used an MAO inhibitor in the last 14 days, such as Nardil or Parnate. This could cause life-threatening side effects. You will also be unable to take Buspar if you have liver or kidney disease. Buspar is classified by the Food and Drug Administration (FDA) as being in the pregnancy category B, which means that it is not likely to harm an unborn baby. However, discuss with your doctor any possible risks of taking Buspar while pregnant as a precaution. Whether or not Buspar appears in breast milk is unknown, therefore do not use Buspar if you are breastfeeding.


  • Buspar may interact with other medications. Tell your doctor about all of the drugs you are taking, both prescription and nonprescription. Buspar may interact with any medications intended for treating a psychiatric disorder, seizure medications, calcium channel blockers, antibiotics, rifampin, ritonavir, dexamethasone, itraconazole and erythromycin. Cold medications, narcotic pain drugs, sleeping pills, allergy medications and muscle relaxants can increase sleepiness when used with Buspar.

Special Considerations

  • Buspar is not intended for use in children under 18 years of age. Unless your doctor instructs you otherwise, do not use Buspar for longer than four weeks. Buspar may impair cognitive activity and reaction time, so use caution while driving. Refrain from drinking alcohol while on this medication, as it may intensify some side effects. Do not consume grapefruit or grapefruit juice, as this may cause dangerous side effects. If you already regularly consume grapefruit products, discuss this with your doctor before cutting them out of your diet.

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