OTC Drugs for Joint Pain

Though there are lots of brands of OTC (over-the-counter) medications for pain on the drugstore shelves, there really aren't that many different drugs available. In the United States, the ones most often used for joint pain are ibuprofen, naproxen, aspirin and acetaminophen. They are all sold in various brands and strengths for pain relief.

  1. Ibuprophen

    • Motrin and Advil are two popular brands of ibuprofen, but it is also sold generically under store brands. It is commonly used for pain in the joints since it relieves inflammation. Doses of ibuprofen over 400 mg are available by prescription. Ibuprofen may cause stomach problems in some, ranging from minor nausea and heartburn to bleeding ulcers. Patients taking ibuprofen regularly should inform their physicians of its use.

    Naproxen

    • Naproxen is most commonly sold under the brand Aleve. It is a non-steroidal anti-inflammatory (NSAID), like ibuprophen. While the two are in the same class of drugs, they are slightly different. Naproxen lasts a bit longer than ibuprophen so you can take a pill twice daily instead of every four to six hours for joint pain. Naproxen is also available in prescription strengths and sold under the names Anaprox and Naprosyn. It may cause similar gastrointestinal problems to that of ibuprofen. In addition, Naproxn may interfere with blood pressure medications.

    Aspirin

    • Aspirin, also known as acetylsalicylic acid, is also a NSAID. It reduces pain, fever and inflammation. Aspirin is sold in 81 mg (known as "baby aspirin"), 325 mg, and 500 mg doses. It can reduce the risk of stroke and possibly prevent heart attack so a baby aspirin is sometimes recommended for those at risk. Aspirin can also cause medical problems, including increased bleeding, ulcers and nausea.

    Acetaminophen

    • Acetaminophen, which is most known under the brand name Tylenol, is an over-the-counter analgesic. It helps to eliminate pain. Acetaminophen is also an antipyretic as it can reduce fever. It does not, however, have any effect on inflammation. Acetaminophen is available in varying formulas and strengths, including extra strength and extended relief formulas. The only major problem with acetaminophen use is possible liver failure in those taking more than the recommended dose or taking the medication for extended periods of time.

    Considerations

    • Acetaminophen does not reduce swelling or redness within the joint. If inflammation is present, acetaminophen would not be a good choice unless it is used in conjunction with an anti-inflammatory. Ibuprophen, naproxen and aspirin can all reduce inflammation and swelling. Consider the benefits and risks of OTC drugs for joint pain and discuss them with a health professional.

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