Olfen Side Effects


Olfen, a nonsteroidal and anti-inflammatory drug (NSAID), is available in some countries, including China, Egypt, Portugal, Poland and Israel. In Australia and New Zealand, Olflen is an approved over-the-counter treatment for fever. Used to treat common infections and minor aches and pains, Olfen is an NSAID known for having fewer side effects than others, but you should always be aware of the function and side effects of any drug you are taking.


  • Olfen goes under the generic name of Diclofenac; brand names include Dedolor and Zolterol, among others. Olfen is used to treat arthritis and gout and to manage pain such as acute migraine and postoperative pain. It is also effective in relieving menstrual pain. Gastrointestinal problems such as upset stomach and stomach ulcers and bleeding are the common side effects associated with Olfen.

Side Effects

  • The side effects of Olfen are related to the cardiac (heart), gastrointestinal, hepatic (liver) and renal (kidney) systems of the body. According to Absoluteastronomy.com, a review study done by the Food and Drug Administration in 2006 concluded that Olfen (Diclofenac) can increase the risk of heart attack.

Gastrointestinal Side Effects

  • Gastrointestinal side effects include stomach upset and bleeding ulcers. Prolonged blood-clotting time and anemia may also develop with long-term Olfen therapy. This medication will be discontinued by your physician's order if ulcer and or bleeding occur. Usually an ulcer-preventative drug is prescribed at bedtime to avoid these side effects. Olfen can also disrupt the normal menstrual cycle.

Side Effects Affecting the White Blood Cells

  • Side effects affecting the white blood cells may occur and can be quite serious. They include leucopenia, or a decrease in the number of white blood cells in the blood. White bloods cells are needed to fight infections. The other is agranulocytosis, or severe leucopenia. These conditions are life-threatening and can be fatal if not diagnosed and treated in the early stages.

Additional Side Effects

  • Infrequently liver damage may also occur. Liver function tests are done to monitor the function of the liver during long-term treatment with Olfen. According to Absoluteastronomy.com, "Studies in Pakistan showed that Diclofenac (Olfen) caused acute kidney failure in vultures when they ate the carcasses of animals that had recently been treated with Olfen."


  • There are several contraindications when Olfen should not be taken. Discuss your medical history with your physician to avoid any untoward reaction before taking Olfen. For example, do not take Olfen if you are allergic to it or have had a history of urticara, rhinitis, shock, bronchospasm or after taking aspirin or another NSAID. Do not take Olfen during the third trimester of pregnancy or if you have Crohn's disease or ulcerative colitis.


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