The Side Effects of Progesterone


Progesterone is a a female hormone that is vital in the regulation of ovulation and the menstrual cycle. The main use of the drug is in women who have not yet reached menopause, but at the same time are having trouble getting their periods due to lack of natural progesterone production in the body. As with any other hormonal supplement, there are a series of possible side effects that can come as a result of use.

Common Side Effects

There are a number of common side effects reported by users after beginning use of progesterone. These include mild nausea, stomach cramps, diarrhea, bloating, headache, dizziness, breast pain or tenderness, muscle pain, acne, increased hair growth, muscle pain, sudden changes in weight, vaginal itching, vaginal discharge and feelings of irritability.

Severe Side Effects

Unfortunately, the possibility of severe side effects does occur while using the drug. These severe side effects can include sudden numbness on one side of the body, sudden headache or confusion, pain behind the eyes, vision and balance problems, chest pain, headaches, nausea, stomach pain, clay-colored stools, dark urine, yellowing of the skin and eyes, a breast lump and sudden feelings of depression.

Important Safety Information

Some forms of progesterone have been known to include peanut oil, so if you have any type of allergy to peanuts, it is advisable to stay away from the drug. Please also tell your doctor if you suffer from any of the following ailments before use: a history of heart stroke or blood clots, circulation problems, a hormone-related cancer (such as breast or uterine cancer), abnormal vaginal bleeding, severe liver disease, or if you are pregnant or recently had a miscarriage.


In order to avoid some of the above side effects, it is important to use the drug correctly. Always take the drug in conjunction with doctor's orders and do not exceed dosage instructions. Progesterone is often given in small cycles, sometimes lasting just six to 12 days during each menstrual cycle. It is important to make a strong effort not to miss any doses.


If you experience any of the above side effects, please contact a medical professional immediately.

If an overdose is suspected, head directly to the emergency room and inform a doctor that you may be poisoned.

Always consult a doctor before starting to use progesterone to ensure that the drug is right for you.

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