Celestone Injection Side Effects


Celestone is a type of corticosteroid, a class of powerful drugs that relieve inflammation, pain, itching and allergic reactions. Corticosteroids are available in many different forms, including tablets, oral suspensions and injectables, such as celestone. Doctors prescribe injections of celestone to treat a number of conditions, including skin diseases, eye infections, kidney and respiratory diseases, arthritis and lupus. Despite its effectiveness, celestone is not for everyone as it presents several risks for side effects and complications in some patients.

Common Side Effects

  • The most common side effects of celestone are not normally serious in nature and pose little discomfort. Many patients receiving celestone injections experience an increased appetite, which can lead to weight gain if overeating occurs on a regular basis as a result. Despite increased hunger, patients also frequently report indigestion after meals. Also, many patients undergoing celestone treatments report feelings of nervousness.

Other Side Effects

  • Drospirenone also has the potential to cause a number of other troublesome or annoying, but not dangerous, side effects. Some patients experience gastrointestinal side effects from the injections, such as nausea, while others report issues with skin, such as acne, rashes, dryness and increased sweating. Neurological side effects of celestone include depression, headaches, being overly emotional, mood swings and insomnia.

Drug Interactions

  • There are some medications which produce unwanted side effects when used in conjunction with celestone. For instance, using diuretics along with celestone has the potential to cause a dangerous elevation to blood potassium levels that can damage the heart and other organs. Cyclosporine, a medication used for asthma, may cause convulsions when used with celestone, while the antifungal ketoconazole causes any side effects of celestone to be exacerbated. Using aspirin or other nonsteroidal anti-inflammatory agents like Tylenol or Advil increases the likelihood that you will experience gastrointestinal side effects while taking celestone.


  • In addition to minor side effects and the risk of interactions, celestone has the potential to cause serious medical complications. One major risk of celestone use is that your body may become more susceptible to bacterial and viral infections and that illnesses that are usually mild, like chickenpox, are more serious and possibly life-threatening while taking undergoing celestone injections. Some patients experience dangerous elevations in blood pressure or heart attacks while taking celestone.


  • Because celestone causes increases in blood sugar levels, your doctor will ask you to closely monitor your glucose readings if you are diabetic. Because of the potential cardiovascular side effects, doctors typically do not prescribe celestone to patients with a history of heart disease or congestive heart failure. Corticosteroids like celestone can also make stomach ulcers worse. If used for a prolonged period of time, celestone has the potential to cause osteoporosis. Additionally, pregnant women should not receive celestone injections due to the risk for birth defects.

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