Soloxine Tablets for Dogs
Soloxine, manufactured by Virbac AH, Inc., is a brand name for the drug levothyroxine sodium, used to treat hypothyroidism in dogs. Hypothyroidism may be hereditary or it may develop with no known cause. A dog suffering from untreated hypothyroidism tends to be lethargic and overweight, with dry, scaly skin and a dull, brittle coat. Untreated hypothyroidism can be debilitating. Fortunately, most dogs with this condition can live long and healthy lives with the proper treatment.
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Hypothyroidism
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Soloxine is the most commonly prescribed medication for hypothyroidism. Hypothyroidism is a condition caused by low levels of circulating thyroid hormone. This happens when the thyroid gland stops working properly. The most common cause of hypothyroidism is idiopathic, meaning there is no known cause. Thyroiditis, or inflammation of the thyroid gland, can also cause hypothyroidism, as can thyroid tumors. Thyroiditis can be hereditary.
Hypothyroidism Symptoms
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Dry skin and brittle hair, particularly on the hindquarters or tail, and hair loss not caused by scratching, are some symptoms of hypothyroidism. Weight gain, lethargy and lack of interest in exercise are also signs of hypothyroidism. Breeding dogs may exhibit low libido and shortened or lengthened heat cycles. Facial paralysis, stumbling, weakness and loss of balance may occur as well.
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Dosing and Effects
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The recommended initial dosage is 0.1 mg per 10 lbs. of body weight daily. Soloxine should be stored at temperatures not exceeding 77 degrees F (25 degrees C). Tablets may be given orally or placed in your dog's food. Overdose may produce the symptoms of thyrotoxicosis: hyperactivity and personality change, reduced heat tolerance, increased urine output, and increased hunger and thirst.
Considerations
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Dogs with significant heart disease or hypertension should be given Soloxine with caution, as the drug targets the heart and central nervous system, and sharply increases metabolic rate, which may prove hazardous with those conditions. Soloxine is acquired by prescription only. Its use in pregnant dogs has not been evaluated.
Time Frame
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Your veterinarian will take a blood sample to measure T4 blood levels at approximately four to eight weeks and adjust the dosage if needed. This level is monitored every four weeks, and the dosage is adjusted accordingly until the ideal maintenance level is established. You should see an improvement in your dog within two to four weeks of starting treatment with Soloxine. Changes in the coat may take up to six months. Routine check-ups will be necessary, as your dog will need to take Soloxine for the rest of its life.
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