Malignant Peripheral Nerve Sheath Tumor Treatment

Malignant peripheral nerve sheath tumors (MPNST) are tumors located inside the sheath of a nerve. These tumors are a type of soft-tissue sarcoma. To treat these tumors, a patient sees an oncologist and a neurosurgeon, though a neurosurgeon may also specialize in oncology or have extensive experience in the area to ensure the best possible treatment. Also, patients can benefit greatly from being treated by medical teams that specialize in soft-tissue sarcomas. Treatment of MPNST often involves several steps, depending on the location of the tumor, type of sarcoma, other patient circumstances and overall health.

  1. Types

    • There are three main types of treatment for MPNST. These treatments are surgical removal, radiation and chemotherapy. Doctors often use all three types in combination to create specific individual treatment plans for a patient.

    Surgical Removal

    • The most common treatment for malignant peripheral nerve sheath tumors is surgical resection. Resection of tumors involves the removal of the tumor and surrounding malignant tissue. The doctors analyze the edges of the area removed, and if cancerous cells remain, they excise a little more surrounding tissue. This continues until the tissues the doctors remove are clear of cancer cells, otherwise known as surgically clear borders. This surgical removal technique ensures the best possible prognosis by removing as much of the local cancer as possible.

    Radiation Therapy

    • Radiation is the use of specifically directed ionized radiation in a medical setting. Radiation is a common treatment for these tumors, and is often very effective at different stages. Preoperatively, radiation can reduce the size of a MPNST, making surgery easier for the doctor and therefore reducing the time spent under anesthesia. Intraoperatively, radiation helps doctors achieve clear borders without having to cut out more tissue, which is very important when the tumor is in a peripheral area such as an arm or leg. Clearing the borders without going deeper often saves the patient from an amputation. Postoperatively, radiation can destroy cancer cells that surgery couldn't remove.

    Chemotherapy

    • While chemotherapy is not particularly effective at treating localized MPNST, doctors often use it to treat cancer that has spread to other areas. Chemotherapy, taken either orally or intravenously, involves taking medication that kills cells.

    Considerations

    • MPNST can spread, and they do so, to other areas of the body. Often the lungs are the first area the cancer from these tumors metastasize to, and then the cancer can spread to any other area of the body. MPNST are difficult tumors for doctors to treat, mainly because they are not a common type of cancer. Every treatment plan for MPNST differs based on the patient's specific circumstances and medical needs.

Related Searches

References

Resources

You May Also Like

  • Nerve Sheath Tumors in Dogs

    Nerve sheath tumors are an uncommon, but potentially life-threatening condition affecting man's best friend. Capable of sprouting in benign and malignant form,...

  • Prognosis & Treatment for Nerve Sheath Tumors in Dogs

    Nerve Sheath Tumors (NST) in dogs is a serious, but rare, condition that affects the peripheral nervous system which provides mechanical support...

  • Canine Nerve Sheath Tumor

    Nerve sheath tumors are tumors in a dog that form in the sheath of a peripheral nerve. The sheath is the connective...

  • Schwannoma Treatment

    Surrounding the nerves in the human body is a layer of tissue called the nerve sheath. Contained within this tissue are cells...

  • What Are the Treatments for Schwannoma?

    Schwannomas are tumors that grow within a nerve. These neural tumors arise from the fibers inside the nerve called schwann cells, rather...

  • What Are the Treatments for Nerve Sheath Tumors in Dogs?

    Nerve sheath tumors (NST) are rare in dogs. NSTs may be benign or malignant and originate from the periaxonal Schwann cells (schwannoma)...

  • Sciatic Nerve Tumors

    The sciatic nerve is the longest and widest single nerve in the human body. It runs from the lower back through the...

  • Nerve Sheath Cancer in Dogs

    According to the National Canine Cancer Foundation, one out of three dogs will suffer from some form of cancer, and more than...

  • Sarcoma Tumor on Sciatic Nerve

    Many people suffer with sciatic nerve pain in the lower back and legs. A sarcoma tumor on the sciatic nerve can be...

  • About Schwannoma Nerve Tumors

    Schwannoma tumors are tumors that originate inside the nerve sheath. Unlike neurofibromas that originate from cells in the sheath itself, schwannomas arise...

  • Schwannoma Tumor Treatment

    Schwannoma tumors are slow-growing tumors that grow from inside the nerve sheath. Unlike other neural tumors that arise from the nerve sheath,...

  • Symptoms of Canine Sarcoma

    Symptoms of Canine Sarcoma. Sarcomas are cancerous tumors that affect dogs. They typically occur from various sources, including connective tissue, fat, muscle...

  • Fibrin Sheath Removal

    Constant dialysis requires catheterization. When a person is using that catheter for an extended period of time, a fibrin sheath may grow...

  • Spinal Cancer Prognosis

    Spinal cancer is not one of the more well known types of this potentially fatal disease, and that poses a problem. Many...

  • Schwannoma Growth

    Schwannomas are neural tumors that grow within the nerve sheath. These tumors arise from the schwann cells inside the nerve. Because neural...

  • Benign Tumor on Sciatic Nerve

    If you are experiencing pain in your back and leg, you could have a problem with your sciatic nerve. Your doctor can...

  • Canine Spinal Tumor Causing Lameness

    If your dog is lame, without treatment, the symptoms will get worse as the tumors grow. Surgery and radiation may give your...

  • How to Remove Eyelid Tumors From Dogs

    Most eyelid tumors occur in middle-aged or older dogs and originate from the glands inside the eyelid. The majority of these tumors...

Related Ads

Featured