What Are the Side Effects of Lupron in Children?

Lupron is a prescription medication typically used to treat men with prostate cancer or women with endometriosis or uterine fibroids, but it is also sometimes used in children to stop early puberty. It works by decreasing the sex hormones a child's body produces, which delays sexual development and the onset of menstrual periods in girls. Lupron is given monthly as an injection. Most doctors will stop using Lupron in patients who have reached the normal age of puberty.

  1. Vaginal Side Effects

    • Girls who receive Lupron injections may experience vaginal inflammation, discharge or bleeding and spotting. Some girls also may initially experience some breast enlargement. All these side effects are normal and no cause for concern.

    Acne

    • Boys and girls who receive Lupron may develop acne or oily skin as a side effect of the medication. This is normal and can be treated the same way acne and oily skin in adolescents and adults is treated.

    Pain

    • Pain, irritation or redness at the injection site is a normal side effect of Lupron. Contact your doctor if your child experiences extreme pain or irritation.

    Sexual Maturity

    • In rare cases, Lupron injections may cause increased sexual maturity. Because children receive Lupron to stop early sexual development, be sure to notify your doctor immediately if you notice any symptoms of continued sexual development.

    Other Serious Side Effects

    • Some children receiving Lupron injections may experience fainting or extreme mood changes. These side effects should be reported to a doctor immediately.

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