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Long-Term Effects of Lupron Depot

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By Megan Snider
eHow Contributing Writer
(0 Ratings)

Lupron is a synthetic hormone that decreases testosterone in men and estrogen in women. Little study has been done on the long-term effects of Lupron Depot by researchers; however, a grassroots movement of men and women called the National Lupron Victims Network brings victims of long-term Lupron treatment together. Luprone began as a part of chemotherapy treatment in prostate cancer. Lupron is now used to help those with endometriosis and precocious, or "early onset", puberty in both girls and boys.

    The National Lupron Victims Network

  1. The National Lupron Victims Network, started in 1993, is an independent, grass-roots organization bringing people together from all around the world. Members of the network share problems, side effects and emotional reactions to the negative long-term effects of Lupron Depot. They also warn about the use of Lupron Depot, which actually has the effect to bring on symptoms of other diseases all by itself and may create numerous problems for the long-term patient. The network also clearly states that Lupron Depot has 265 adverse reactions in its own package insert for users. This claim clearly states the danger of Lupron Depot itself, barely touching upon the long-term effects.
  2. Long-Term Effects

  3. The long-term effects will vary between men and women. However, those affected by negative side effects share their struggle with others on the network. Some of the cited effects are eye, bone, heart and immune system damage, heart disorders in infants birthed by mothers on Lupron Depot, bleeding disorders, severe allergies, stunted growth, seizures, degenerative arthritis, osteoporosis, retinal vision loss, worsened and recurrent endometriosis, bone-marrow production problems, anemia, leucopenia and harsh withdrawal side effects.
  4. Rebound Effect

  5. The rebound effect occurs in both traditional and psychiatric medical treatments. Basically, it happens when people abruptly stop their medicine, and all the prior symptoms they had experienced before treatment recur. The recurrence is severe and the initial symptoms are heightened which forces people into horrible spells of withdrawal. Depending on the person and the medicine, the rebound effect may stop or continue with more extreme side effects.
  6. FDA and Lupron Depot

  7. According to The National Lupron Victims Network, over 6,000 reports by women alone have already reached the FDA. These letters are testimonies of horrible experiences with the drug and urge the FDA to do more research into Lupron Depot before it is prescribed to another person. The FDA has studied many adverse effects, but they are in no way willing to stop doctors from prescribing Lupron Depot injections. Lupron Depot is still recognized and approved both by the FDA and doctors.
  8. Conclusion

  9. Try to be cautious in using medicines you are not familiar with. Do research until you are comfortable to try a new drug and go through side effects or possible withdrawal. Being informed will oftentimes keep a person safe against the unknown or rare side effects of a drug.
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