What Is Amlodipine Besylate?

What Is Amlodipine Besylate?
What Is Amlodipine Besylate? (Image: Public Domain)

Amlodipine besylate is a calcium antagonist or a calcium channel blocker. The drug is a type of antihypertensive because it relaxes blood vessels, resulting in lower blood pressure. Lower blood pressure helps reduce the risk of heart attacks, kidney problems and strokes. The drug is prescribed to patients who have heart conditions such as angina and high blood pressure. Amlodipine besylate is marketed under the brand name Norvasc, and it comes in tablet form.

Drug Interactions

Individuals who are prescribed Amlodipine besylate should know that when it's combined with certain other drugs it can increase the risk of side effects. Prescribing physicians should know what medications you take before they prescribe Amlodipine besylate as some combinations of medicine may require special types of tests and dosage considerations or may result in Amlodipine besylate not being prescribed at all.

Existing Health Conditions

There are certain medical conditions that Amlodipine besylate may worsen. Individuals with congestive heart failure should know the drug slightly increases the risk that the condition will get worse. Individuals with liver disease should know that the medication may show up stronger in the blood. For this reason people with liver disease are often prescribed smaller doses of Amlodipine besylate than individuals who have no liver problems. The drug may also worsen low blood pressure.


The dosage instructions will differ from patient to patient and will depend on the patient's health history and the type of condition being treated. Dosage instructions should be followed precisely. Patients should not adjust their dosages unless advised to do so by their physicians. If a dose is missed, it should be taken as soon as possible. However, double-dosing is not advised. Don't take the missed dose if it's almost time for the next dose.


People who take Amlodipine besylate should not suddenly stop taking the drug. Doing so can result in chest pain. It can also result in worsening high blood pressure. A physician will gradually lower the dosage over time to wean the body off of the medication so no harmful effects occur.

Side Effects

Amlodipine besylate may cause side effects, such as swelling of the feet and ankles, stomach pain, headache, sleepiness and flushing. Less common side effects include a pounding heartbeat and dizziness. Rare side effects include dark yellow urine, lightheadedness, slow heartbeat, nausea, chest pain, yellow skin and yellow eyes. All side effects should be promptly reported to a physician.

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