Side Effects of Vitamin B12 Sublingual 2500 mg


Unlike some dietary supplements, Vitamin B12 has a considerable amount of research that supports its impact on human physiology. Vitamin B12 is well accepted by both the allopathic and naturopathic communities as a micro-nutrient capable of supporting a focused mind and improved metabolism of carbohydrates, fats and proteins. Daily sublingual ingestion of Vitamin B12 at 2,500 mcg is often considered a therapeutic level of the supplement and consumers should avoid such a high amount without consulting a practitioner.

The Facts

Vitamin B12 is produced in the intestinal tract by healthy micro-flora but usually in insufficient amounts to maintain optimal health. Therefore, many people supplement their intake with a dietary supplement that uses a sublingual delivery method.


Vitamin B12 is delivered orally, by injection or through tablets that release the vitamin for sublingual absorption. It plays a vital role in digestion and a lack of the nutrient is associated with pernicious anemia.


According to the National Institutes of Health's Office of Dietary Supplements (ODS) the DRI (Dietary Reference Intake) for B12 is 2.4 mcg for adults. A supplement that provides more than 100 times the DRI can appear overly aggressive.


Also known as cyanocobalamin, B12 is a coenzyme, meaning it is required as part of an enzymatic process. It is an essential nutrient despite the fact that it can be created in the bowel.


Individuals needing to supplement their diet with Vitamin B12 will often use supplements in the 1,000-to-2,500 mcg range to offset the poor absorption rates of dietary supplements and to offset the existing deficiency.

Side Effects

The body is extremely inefficient when it comes to absorbing large amounts of nutrients. Side effects from Vitamin B12 delivered sublingually are rare and are most-often related to an allergy associated with another ingredient in the dietary supplement.


All consumers considering supplementing their diets should speak to their doctor about possible complications due to existing conditions, prescription medication or other supplements.

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